Learn how analyze complex ion mobility spectrometry-mass spectrometry (IMS-MS) small molecule data using spectral libraries and ion mobility filtering. Explore a spectral library containing m/z, retention time, fragmentation, and ion mobility information, and learn how the CCS values for each molecule are used to increase the selectivity of precursor and fragment extracted ion chromatograms. (23 pages)
Also, see our paper in Nature Protocols (please cite) Utilizing Skyline to analyze lipidomics data containing liquid chromatography, ion mobility spectrometry and mass spectrometry dimensions [abstract]